3 pips – Stepping across this dice will reroll all pickups and trinkets on the entire floor.So, if you have any pickups in the Dice Room, be sure not to pick them up unless it’s something you need. 2 pips – Triggers the D20 effect, where it will reroll all the pickups in the room.1 pip – When you step onto this, you will reroll your character’s collected items into random ones, much like how the D4 would.Related: Binding of Isaac Repentance Item Guide – False PHD The effects that occur in the Dice Room in the Binding of Isaac The effect will only happen once, so if you try to step on the Dice again, nothing will happen. The effect that happens will depend on the number of pips that were shown. When you step onto the Dice in the center of the room, the room will shake, and an effect will occur. The Dice Room will have one to six pips on the Dice. This strange room is called the Dice Room. Occasionally, you may stumble upon a red room with Dice in the center. Although you’ll be navigating the same stages, the enemies, layouts, and rooms will be different each time. The Binding of Isaac is a randomly generated dungeon crawler with rogue-like elements.
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